Cheryl A Frye Selected Research

2,3,4,5- Tetrahydro- 7,8- dihydroxy- 1- phenyl- 1H- 3- benzazepine (SKF 38393)

1/2010	Infusions of anti-sense oligonucleotides for DARPP-32 to the ventral tegmental area reduce effects of progesterone- and a dopamine type 1-like receptor agonist to facilitate lordosis.
9/2008	Activity of protein kinase C is important for 3alpha,5alpha-THP's actions at dopamine type 1-like and/or GABAA receptors in the ventral tegmental area for lordosis of rats.
9/2008	In the ventral tegmental area, progestogens' membrane-mediated actions for lordosis of rats involve the second-messenger phospholipase C.
9/2006	Progestins' effects on sexual behaviour of female rats and hamsters involving D1 and GABA(A) receptors in the ventral tegmental area may be G-protein-dependent.
8/2006	In the ventral tegmental area, progestins have actions at D1 receptors for lordosis of hamsters and rats that involve GABA A receptors.
6/2006	In the ventral tegmental area, G-proteins mediate progesterone's actions at dopamine type 1 receptors for lordosis of rats and hamsters.
1/2006	In the ventral tegmental area, progestins' membrane-mediated actions for lordosis of hamsters and rats involve protein kinase A.
6/2005	Progestin-facilitated lordosis of hamsters may involve dopamine-like type 1 receptors in the ventral tegmental area.
7/2004	Progestins' actions in the VTA to facilitate lordosis involve dopamine-like type 1 and 2 receptors.
1/2004	In the ventral tegmental area, G-proteins and cAMP mediate the neurosteroid 3alpha,5alpha-THP's actions at dopamine type 1 receptors for lordosis of rats.

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Cheryl A Frye Research Topics

Disease

36	Lordosis 01/2020 - 08/2002
14	Seizures (Absence Seizure) 11/2021 - 03/2004
9	Epilepsy (Aura) 07/2014 - 03/2004
4	Neoplasms (Cancer) 03/2011 - 03/2006
4	Breast Neoplasms (Breast Cancer) 02/2010 - 04/2009
4	Shock 05/2008 - 07/2003
3	Alzheimer Disease (Alzheimer's Disease) 06/2009 - 06/2006
2	Substance-Related Disorders (Drug Abuse) 01/2011 - 01/2011
2	Schizophrenia (Dementia Praecox) 01/2011 - 05/2010
2	Pain (Aches) 01/2011 - 04/2004
2	Autistic Disorder (Autism) 06/2010 - 06/2010
2	Partial Epilepsies (Epilepsy, Partial) 11/2006 - 07/2004
1	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 01/2018
1	Alopecia (Baldness) 01/2018
1	Premature Birth (Birth, Premature) 11/2011
1	Anxiety Disorders (Anxiety Disorder) 01/2011
1	Mental Disorders (Mental Disorder) 01/2011
1	Endocrine Gland Neoplasms (Cancer, Endocrine) 02/2010
1	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 01/2010
1	Gambling (Pathological Gambling) 01/2010

Drug/Important Bio-Agent (IBA)

32	Progesterone FDA LinkGeneric 07/2014 - 01/2003
23	Progestins (Progestagens)IBA 03/2014 - 01/2003
12	Dopamine (Intropin)FDA LinkGeneric 01/2010 - 01/2004
11	Hormones (Hormone)IBA 07/2014 - 08/2002
11	NeurosteroidsIBA 01/2011 - 01/2004
11	GABA-A Receptors (GABA(A) Receptor)IBA 01/2011 - 01/2003
11	SteroidsIBA 01/2011 - 03/2004
10	Estradiol (Delestrogen)FDA LinkGeneric 03/2014 - 01/2004
10	2,3,4,5- Tetrahydro- 7,8- dihydroxy- 1- phenyl- 1H- 3- benzazepine (SKF 38393)IBA 01/2010 - 01/2004
8	Estrogens (Estrogen)FDA Link 07/2014 - 04/2004
8	gamma-Aminobutyric Acid (GABA)IBA 07/2010 - 03/2005
7	Pregnanolone (Allopregnanolone)IBA 11/2021 - 10/2002
7	Progesterone Receptors (Progesterone Receptor)IBA 03/2014 - 01/2004
6	AndrogensIBA 07/2010 - 07/2004
5	BicucullineIBA 01/2020 - 05/2005
5	GTP-Binding Proteins (G-Protein)IBA 10/2008 - 01/2004
5	glutathione-bicarbonate-Ringer solution (BSS plus)FDA LinkGeneric 10/2008 - 01/2006
5	MuscimolIBA 09/2008 - 01/2006
4	N,N- di- n- hexyl- 2- (4- fluorophenyl)indole- 3- acetamideIBA 01/2014 - 01/2003
4	Pentylenetetrazole (Metrazol)IBA 08/2005 - 12/2004
3	Dizocilpine Maleate (Dizocilpine)IBA 01/2020 - 02/2007
3	Testosterone (Sustanon)FDA Link 01/2018 - 07/2004
3	Type C PhospholipasesIBA 10/2008 - 09/2008
3	Anticonvulsants (Antiepileptic Drugs)IBA 11/2006 - 07/2004
3	guanosine 5'-O-(2-thiodiphosphate)IBA 09/2006 - 01/2004
3	SCH 23390IBA 06/2005 - 01/2004
2	Dihydrotestosterone (Androstanolone)IBA 01/2018 - 09/2005
2	PK 11195 (PK11195)IBA 01/2014 - 01/2003
2	N-Methylaspartate (NMDA)IBA 01/2014 - 02/2007
2	Steroid Receptors (Steroid Receptor)IBA 01/2011 - 01/2010
2	Fluoxetine (Prozac)FDA LinkGeneric 08/2010 - 12/2003
2	Proteins (Proteins, Gene)FDA Link 02/2010 - 01/2008
2	Antisense OligonucleotidesIBA 01/2010 - 01/2008
2	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 10/2008 - 01/2006
2	Adenylyl Cyclases (Adenylyl Cyclase)IBA 10/2008 - 08/2006
2	estradiol 3-benzoate (estradiol benzoate)IBA 02/2007 - 01/2003
2	Lamotrigine (Lamictal)FDA LinkGeneric 11/2006 - 07/2004
2	EnzymesIBA 08/2006 - 07/2004
2	Adenosine (Adenocard)FDA LinkGeneric 01/2006 - 01/2004
2	QuinpiroleIBA 06/2005 - 07/2004
2	Sulpiride (neogama)IBA 06/2005 - 07/2004
1	Anti-Anxiety Agents (Anxiolytics)IBA 01/2020
1	Finasteride (Propecia)FDA LinkGeneric 01/2018
1	Saline SolutionIBA 11/2011
1	LipopolysaccharidesIBA 11/2011
1	CarcinogensIBA 03/2011
1	Kainic Acid (Kainate)IBA 02/2011
1	CannabinoidsIBA 01/2011
1	Vitamin D FDA LinkGeneric 01/2011
1	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 01/2011
1	Adrenal Cortex Hormones (Corticosteroids)IBA 06/2010
1	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 05/2010
1	alpha-Fetoproteins (alpha-Fetoprotein)IBA 02/2010
1	salicylhydroxamic acid (SHAM)IBA 02/2010
1	Oxidopamine (6 Hydroxydopamine)IBA 02/2010
1	Peptides (Polypeptides)IBA 02/2010
1	Oxytocin Receptors (Oxytocin Receptor)IBA 01/2010
1	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2010
1	GlobulinsIBA 01/2010
1	Oxytocin (Pitocin)FDA LinkGeneric 01/2010
1	Estrogen ReceptorsIBA 08/2009
1	Oxidoreductases (Dehydrogenase)IBA 08/2009
1	trilostane FDA Link 08/2009
1	Tamoxifen FDA LinkGeneric 08/2009
1	Protein Kinase CIBA 09/2008
1	bisindolylmaleimideIBA 09/2008
1	1- (6- ((3- methoxyestra- 1,3,5(10)- trien- 17- yl)amino)hexyl)- 1H- pyrrole- 2,5- dioneIBA 09/2008
1	LY 235959IBA 09/2008
1	AcidsIBA 09/2008
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 09/2008
1	Conjugated (USP) Estrogens (Premarin)FDA Link 05/2008
1	Estrogen Receptor betaIBA 01/2008
1	Protein Isoforms (Isoforms)IBA 01/2008
1	Amyloid (Amyloid Fibrils)IBA 01/2008
1	Presenilin-1IBA 01/2008
1	Estrogen Receptor alphaIBA 01/2008
1	NMDA receptor A1IBA 02/2007

Therapy/Procedure

3	Therapeutics 07/2014 - 04/2009
1	Injections 01/2010
1	Intraperitoneal Injections 09/2008